Rome is the capital city and a special comune of Italy (named Comune di Roma Capitale). Rome also serves as the capital of the Lazio region. With 2,872,800 residents in 1,285 km2(496.1 sq mi), it is also the country's most populated comune. It is the fourth-most populous city in the European Union by population within city limits. It is the centre of the Metropolitan City of Rome, which has a population of 4,355,725 residents, thus making it the most populous metropolitan city in Italy. Rome is located in the central-western portion of the Italian Peninsula, within Lazio (Latium), along the shores of the Tiber. The Vatican City (the smallest country in the world) is an independent country inside the city boundaries of Rome, the only existing example of a country within a city: for this reason Rome has been often defined as capital of two states.

Rome's history spans 28 centuries. While Roman mythology dates the founding of Rome at around 753 BC, the site has been inhabited for much longer, making it one of the oldest continuously occupied sites in Europe. The city's early population originated from a mix of Latins, Etruscans, and Sabines. Eventually, the city successively became the capital of the Roman Kingdom, the Roman Republic and the Roman Empire, and is regarded as the birthplace of Western civilization and by some as the first ever metropolis. It was first called The Eternal City (Latin: Urbs Aeterna; Italian: La Città Eterna) by the Roman poet Tibullus in the 1st century BC, and the expression was also taken up by Ovid, Virgil, and Livy. Rome is also called the "Caput Mundi" (Capital of the World). After the fall of the Western Empire, which marked the beginning of the Middle Ages, Rome slowly fell under the political control of the Papacy, which had settled in the city since the 1st century AD, until in the 8th century it became the capital of the Papal States, which lasted until 1870. Beginning with the Renaissance, almost all the popes since Nicholas V (1447–1455) pursued over four hundred years a coherent architectural and urban programme aimed at making the city the artistic and cultural centre of the world. In this way, Rome became first one of the major centres of the Italian Renaissance, and then the birthplace of both the Baroque style and Neoclassicism. Famous artists, painters, sculptors and architects made Rome the centre of their activity, creating masterpieces throughout the city. In 1871, Rome became the capital of the Kingdom of Italy, which, in 1946, became the Italian Republic.

Rome has the status of a global city. In 2016, Rome ranked as the 14th-most-visited city in the world, 3rd most visited in the European Union, and the most popular tourist attraction in Italy. Its historic centre is listed by UNESCO as a World Heritage Site. The famous Vatican Museums are among the world's most visited museums while the Colosseum was the most popular tourist attraction in world with 7.4 million visitors in 2018. Host city for the 1960 Summer Olympics, Rome is the seat of several specialized agencies of the United Nations, such as the Food and Agriculture Organization (FAO), the World Food Programme (WFP) and the International Fund for Agricultural Development (IFAD). The city also hosts the Secretariat of the Parliamentary Assembly of the Union for the Mediterranean (UfM) as well as the headquarters of many international business companies such as Eni, Enel, TIM, Leonardo S.p.A., and national and international banks such as Unicredit and BNL. Its business district, called EUR, is the base of many companies involved in the oil industry, the pharmaceutical industry, and financial services. Rome is also an important fashion and design centre thanks to renowned international brands centered in the city. Rome's Cinecittà Studios have been the set of many Academy Award–winning movies.

Salerno is one of the most popular seaside cities in Italy, intended for recreation at sea. The climate here is warm and mild, which is typical for all cities of the Neapolitan Riviera. Tourism in Salerno is at a high level, as the city is a rich historical and cultural center. Salerno contains many attractions interesting for lovers of history, art and culture.

Sicily is the largest island in the Mediterranean Sea and one of the 20 regions of Italy. It is one of the five Italian autonomous regions, in Southern Italy along with surrounding minor islands, officially referred to as Regione Siciliana.

Sicily is located in the central Mediterranean Sea, south of the Italian Peninsula, from which it is separated by the narrow Strait of Messina. Its most prominent landmark is Mount Etna, the tallest active volcano in Europe, and one of the most active in the world, currently 3,329 m (10,922 ft) high. The island has a typical Mediterranean climate.

The earliest archaeological evidence of human activity on the island dates from as early as 12,000 BC. By around 750 BC, Sicily had three Phoenician and a dozen Greek colonies and, for the next 600 years, it was the site of the Sicilian Wars and the Punic Wars. After the fall of the Roman Empire in the 5th century AD, Sicily was ruled during the Early Middle Ages by the Vandals, the Ostrogoths, the Byzantine Empire, and the Emirate of Sicily. The Norman conquest of southern Italy led to the creation of the Kingdom of Sicily, which was subsequently ruled by the Hohenstaufen, the Capetian House of Anjou, Spain, and the House of Habsburg. It was finally unified under the House of Bourbon with the Kingdom of Naples as the Kingdom of the Two Sicilies. It became part of Italy in 1860 following the Expedition of the Thousand, a revolt led by Giuseppe Garibaldi during the Italian unification, and a plebiscite. Sicily was given special status as an autonomous region on 15th May 1946, 18 days before the Italian constitutional referendum of 1946. Albeit, much of the autonomy still remains unapplied, especially financial autonomy, because the autonomy-activating laws have been deferred to be approved by the parithetic committee (50% Italian State, 50% Regione Siciliana), since 1946.

Sicily has a rich and unique culture, especially with regard to the arts, music, literature, cuisine, and architecture. It is also home to important archaeological and ancient sites, such as the Necropolis of Pantalica, the Valley of the Temples, Erice and Selinunte.

Ajaccio  is a French commune, prefecture of the department of Corse-du-Sud, and head office of the Collectivité territoriale de Corse (capital city of Corsica). It is also the largest settlement on the island. Ajaccio is located on the west coast of the island of Corsica, 210 nautical miles (390 km) southeast of Marseille.

The original city went into decline in the Middle Ages, but began to prosper again after the Genoese built a citadel in 1492 to the south of the earlier settlement. After the Corsican Republic was declared in 1755 the Genoese continued to hold several citadels, including Ajaccio, until the French took control of the island.

The inhabitants of the commune are known as Ajacciens or Ajacciennes. The most famous of these is Napoleon Bonaparte who was born in Ajaccio in 1769, and whose ancestral home, the Maison Bonaparte, is now a museum. Other dedications to him in the city include Ajaccio Napoleon Bonaparte Airport.

Cannes is a city located on the French Riviera. It is a commune located in the Alpes-Maritimes department, and host city of the annual Cannes Film Festival, Midem, and Cannes Lions International Festival of Creativity. The city is known for its association with the rich and famous, its luxury hotels and restaurants, and for several conferences. On 3 November 2011 it also played host to the G20 organisation of industrialised nations.

The town of Sete, located in the south of France between the Thau Lagoon and the Mediterranean Sea, is often called the "Venice of Languedoc" thanks to its picturesque canals, where fishing boats and tour boats bustle about. Founded in the 17th century as a port for the Canal du Midi, Sète remains an important fishing and commercial hub. The city is overlooked by Mount Saint-Clair, which offers panoramic views of the surrounding area, including endless salt flats and the azure waters of the gulf.

Sète is known not only for its maritime charm but also for its rich cultural life. It is the birthplace of poet Paul Valéry, who is commemorated by a museum and a marine cemetery where he is buried. In summer, the city hosts a unique celebration — water jousting tournaments (joutes nautiques), a tradition dating back to the Middle Ages. The local cuisine is renowned for its fresh seafood, especially oysters and mussels from the lagoon. Sète is a place where Mediterranean spirit, history, gastronomy, and poetry come together.

Mallorca is the largest island in the Balearic Islands, which are part of Spain and located in the Mediterranean. The native language, as on the rest of the Balearic Islands, is Catalan, which is co-official with Spanish.

The capital of the island, Palma, is also the capital of the autonomous community of the Balearic Islands. The Balearic Islands have been an autonomous region of Spain since 1983. There are two small islands off the coast of Mallorca: Cabrera (southeast of Palma) and Dragonera (west of Palma). The anthem of Mallorca is "La Balanguera".

Like the other Balearic Islands of Menorca, Ibiza and Formentera, the island is an extremely popular holiday destination, particularly for tourists from Germany and the United Kingdom. The international airport, Palma de Mallorca Airport, is one of the busiest in Spain; it was used by 28.0 million passengers in 2017, increasing every year since 2012.

The name derives from Classical Latin insula maior, "larger island". Later, in Medieval Latin, this became Maiorica, "the larger one", in comparison to Menorca, "the smaller one".

Barcelona is a city in Spain. It is the capital and largest city of Catalonia, as well as the second most populous municipality of Spain. With a population of 1.6 million within city limits, its urban area extends to numerous neighbouring municipalities within the Province of Barcelona and is home to around 4.8 million people, making it the sixth most populous urban area in the European Union after Paris, London, Madrid, the Ruhr area and Milan. It is one of the largest metropolises on the Mediterranean Sea, located on the coast between the mouths of the rivers Llobregat and Besòs, and bounded to the west by the Serra de Collserola mountain range, the tallest peak of which is 512 metres (1,680 feet) high.

Founded as a Roman city, in the Middle Ages Barcelona became the capital of the County of Barcelona. After merging with the Kingdom of Aragon, Barcelona continued to be an important city in the Crown of Aragon as an economic and administrative centre of this Crown and the capital of the Principality of Catalonia. Barcelona has a rich cultural heritage and is today an important cultural centre and a major tourist destination. Particularly renowned are the architectural works of Antoni Gaudí and Lluís Domènech i Montaner, which have been designated UNESCO World Heritage Sites. The headquarters of the Union for the Mediterranean are located in Barcelona. The city is known for hosting the 1992 Summer Olympics as well as world-class conferences and expositions and also many international sport tournaments.

Barcelona is one of the world's leading tourist, economic, trade fair and cultural centres, and its influence in commerce, education, entertainment, media, fashion, science, and the arts all contribute to its status as one of the world's major global cities. It is a major cultural and economic centre in southwestern Europe, 24th in the world (before Zürich, after Frankfurt) and a financial centre. In 2008 it was the fourth most economically powerful city by GDP in the European Union and 35th in the world with GDP amounting to €177 billion. In 2012 Barcelona had a GDP of $170 billion; and it was leading Spain in employment rate in that moment.

In 2009 the city was ranked Europe's third and one of the world's most successful as a city brand. In the same year the city was ranked Europe's fourth best city for business and fastest improving European city, with growth improved by 17% per year, and the city has been experiencing strong and renewed growth for the past three years. Since 2011 Barcelona has been a leading smart city in Europe. Barcelona is a transport hub, with the Port of Barcelona being one of Europe's principal seaports and busiest European passenger port, an international airport, Barcelona–El Prat Airport, which handles over 50 million passengers per year, an extensive motorway network, and a high-speed rail line with a link to France and the rest of Europe.